BSG monoclonal antibody, clone MEM-M6/1 (FITC)
产品名称： BSG monoclonal antibody, clone MEM-M6/1 (FITC)
英文名称： BSG monoclonal antibody, clone MEM-M6/1 (FITC)
产品编号： MAB5049
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against recombinant BSG.
- Immunogen:
- Recombinant Fc fusion protein corresponding to BSG.
- Host:
- Mouse
- Theoretical MW (kDa):
- 50-60
- Reactivity:
- Human
- Specificity:
- This antibody recognizes an epitope in the N-terminal Ig domain (D1) of CD147 (Neurothelin), a 50-60 KDa type I transmembrane glycoprotein primarily expressed on all leukocytes, red blood cells, platelets and endothelial cells; it is not expressed by resting lymphocytes. This antibody is a high-affinity antibody capable of binding to unstimulated peripheral blood T cells.
- Form:
- Liquid
- Conjugation:
- FITC
- Isotype:
- IgG1
- Storage Buffer:
- In PBS (0.2% BSA, 15 mM sodium azide)
- Storage Instruction:
- Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Extracellular matrix metalloproteinase inducer (CD147) is a novel receptor on platelets, activates platelets, and augments nuclear factor kappaB-dependent inflammation in monocytes.
Schmidt R, Bultmann A, Fischel S, Gillitzer A, Cullen P, Walch A, Jost P, Ungerer M, Tolley ND, Lindemann S, Gawaz M, Schomig A, May AE.Circ Res. 2008 Feb 15;102(3):302-9. Epub 2007 Nov 29.
- 2.
- Cyclophilin B induces integrin-mediated cell adhesion by a mechanism involving CD98-dependent activation of protein kinase C-delta and p44/42 mitogen-activated protein kinases.
Melchior A, Denys A, Deligny A, Mazurier J, Allain F.Exp Cell Res. 2008 Feb 1;314(3):616-28. Epub 2007 Nov 17.
- 3.
- T cell activation-associated epitopes of CD147 in regulation of the T cell response, and their definition by antibody affinity and antigen density.
Koch C, Staffler G, Huttinger R, Hilgert I, Prager E, Cerny J, Steinlein P, Majdic O, Horejsi V, Stockinger H.Int Immunol. 1999 May;11(5):777-86.
- Application Image
- Flow Cytometry
- Entrez GeneID:
- 682
- Gene Name:
- BSG
- Gene Alias:
- 5F7,CD147,EMMPRIN,M6,OK,TCSF
- Gene Description:
- basigin (Ok blood group)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. The encoded protein is also a member of the immunoglobulin superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- CD147 antigen,M6 leukocyte activation antigen,OK blood group antigen,basigin,collagenase stimulatory factor,extracellular matrix metalloproteinase inducer
- Related Disease