DDX54,ATP依赖RNA解旋酶DDX54抗体

产品编号HZ-14353R
英文名称DDX54
中文名称ATP依赖RNA解旋酶DDX54抗体
别 名2410015A15Rik; AI414901; ATP dependent RNA helicase DDX54; ATP-dependent RNA helicase DDX54; ATP-dependent RNA helicase DP97; DDX54; DDX54_HUMAN; DEAD (Asp-Glu-Ala-Asp) box polypeptide 54; DEAD box protein 54; DEAD box RNA helicase 97 kDa; DP97; MGC2835; RGD1562539.
说 明 书0.1ml 0.2ml
研究领域发育生物学 转运蛋白 细胞分化 表观遗传学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Pig, Cow, Horse, Sheep,
DDX54,ATP依赖RNA解旋酶DDX54抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量99kDa
细胞定位细胞核
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human DDX54
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
DDX54,ATP依赖RNA解旋酶DDX54抗体PubMedPubMed
产品介绍background:
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The nucleolar protein encoded by this gene interacts in a hormone-dependent manner with nuclear receptors, and represses their transcriptional activity. Alternative splice variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors.

Subcellular Location:
Nucleus > nucleolus.

Similarity:
Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
Contains 1 helicase ATP-binding domain.
Contains 1 helicase C-terminal domain.

Gene ID:
79039

Database links:
Entrez Gene: 79039 Human
Omim: 611665 Human
SwissProt: Q8TDD1 Human
Unigene: 506861 Human

DDX54,ATP依赖RNA解旋酶DDX54抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.