NFKB2,p52,p100-Specific抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
NFKB2,p52,p100-Specific抗体

NFKB2,p52,p100-Specific抗体

商家询价

产品名称： NFKB2,p52,p100-Specific抗体

英文名称： NFKB2,p52,p100-SpecificAntibody

产品编号： XY15503-1-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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  • 地址 : 上海市闵行莘庄工业区春东路508号A1-2F
  • 邮编 : 200612
  • 所在区域 : 上海
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 NFKB2,P52,P100-SPECIFIC抗体Applications

Tested Applications: ELISA, IHC, WB
Specificity Reaction: Human, Mouse; Other species are not tested.Please decide the specificity by homology
Positive WB detected in A431 cells, HeLa cells, MCF-7 cells, mouse heart tissue
Positive IHC detected in Human testis tissue, human brain tissue, human kidney tissue, human lung tissue, human ovary tissue, human placenta tissue, human spleen tissue
Recommended dilution WB : 1:200-1:2000
IHC : 1:20-1:200
 NFKB2,P52,P100-SPECIFIC抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Images
Prev1NextView more validation data
  • 15503-1-AP;H-testisImmunohistochemical of paraffin-embedded human testis using 15503-1-AP(NFKB2,p52,p100-Specific antibody) at dilution of 1:50 (under 40x lens)
  • 15503-1-AP;human spleen tissueImmunohistochemical of paraffin-embedded human spleen using 15503-1-AP(NFKB2,p52,p100-Specific antibody) at dilution of 1:50 (under 40x lens)
  • 15503-1-AP;A431 cellsA431 cells were subjected to SDS PAGE followed by western blot with 15503-1-AP( NFKB2,p52,p100-Specific Antibody) at dilution of 1:600
Product Information NFKB2,P52,P100-SPECIFIC抗体
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen Information
Immunogen: Peptide Full Name: Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
Caculated Molecular
Weight:		 97 kDa Observed Molecular 
Weight:		 52/100kd
GenbankNo NM_001077494 GeneID: 4791
Symbol NFKB2 Synonyms DNA binding factor KBF2, H2TF1, LYT 10, LYT10, NFKB2, NFKB2,p100, NFKB2,p52,p100, Oncogene Lyt 10, p100, p52
Background

NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. NFKB2 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p100 and generation of p52 by a cotranslational processing. The proteasome-mediated process ensures the production of both p52 and p100 and preserves their independent function. P52 binds to the kappa-B consensus sequence 5'-GGRNNYYCC-3', located in the enhancer region of genes involved in immune response and acute phase reactions. P52 and p100 are respectively the minor and major form; the processing of p100 being relatively poor. Isoform p49 is a subunit of the NF-kappa-B protein complex, which stimulates the HIV enhancer in synergy with p65. This antibody can bind both p52 and p100 isoforms of NFKB2. NFKB2,P52,P100-SPECIFIC抗体

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