Stat5a polyclonal antibody
产品名称： Stat5a polyclonal antibody
英文名称： Stat5a polyclonal antibody
产品编号： PAB11328
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of Stat5a.
- Immunogen:
- A synthetic peptide corresponding to C-terminus of mouse Stat5a.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Specificity:
- This antibody is specific to mouse Stat5 protein.
- Form:
- Liquid
- Storage Buffer:
- In 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:25000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Direct glucocorticoid receptor-Stat5 interaction in hepatocytes controls body size and maturation-related gene expression.
Engblom D, Kornfeld JW, Schwake L, Tronche F, Reimann A, Beug H, Hennighausen L, Moriggl R, Schutz G.Genes Dev. 2007 May 15;21(10):1157-62.
- 2.
- The modulation of STAT5A/GR complexes during fat cell differentiation and in mature adipocytes.
Baugh JE Jr, Floyd ZE, Stephens JM.Obesity (Silver Spring). 2007 Mar;15(3):583-90.
- 3.
- Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation.
Laurence A, Tato CM, Davidson TS, Kanno Y, Chen Z, Yao Z, Blank RB, Meylan F, Siegel R, Hennighausen L, Shevach EM, O'shea JJ.Immunity. 2007 Mar;26(3):371-81.
- Applications
- Western Blot (Cell lysate)
- Western blot using Stat5a polyclonal antibody (Cat # PAB11328) shows detection of Stat5a protein in HeLa cell extract (arrowhead). Primary antibody was used at a 1 : 600 dilution reacted overnight at 4°C. Secondary antibody was used at 1 : 20,000. Molecular weight estimation was made by comparison to prestained MW markers. Identity of the upper and lower bands is unknown.
Personal communication, Luanne Lukes, NCI, Bethesda, MD.
- Entrez GeneID:
- 20850
- Protein Accession#:
- NP_035618;P42230
- Gene Name:
- Stat5a
- Gene Alias:
- AA959963,STAT5
- Gene Description:
- signal transducer and activator of transcription 5A
- Gene Ontology:
- Hyperlink
- Other Designations:
- OTTMUSP00000002045,OTTMUSP00000002046,STAT5a variant delta E18,mammary gland factor STAT5A
- Interactome
