GDNF polyclonal antibody
产品名称： GDNF polyclonal antibody
英文名称： GDNF polyclonal antibody
产品编号： PAB11658
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of GDNF.
- Immunogen:
- A synthetic peptide corresponding to amino acids 186-205 of human GDNF.
- Host:
- Rabbit
- Theoretical MW (kDa):
- 15
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Immunoaffinity purification
- Concentration:
- Lot specific
- Storage Buffer:
- In 10 mM PBS, pH 7.4 (1% BSA, 0.1% sodium azide)
- Storage Instruction:
- Store at 4°C.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 2668
- Gene Name:
- GDNF
- Gene Alias:
- ATF1,ATF2,HFB1-GDNF
- Gene Description:
- glial cell derived neurotrophic factor
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. In addition to the transcript encoding GDNF, two additional alternative transcripts encoding distinct proteins, referred to as astrocyte-derived trophic factors, have also been described. Mutations in this gene may be associated with Hirschsprung disease. [provided by RefSeq
- Other Designations:
- astrocyte-derived trophic factor,glial cell line derived neurotrophic factor,glial derived neurotrophic factor
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