BAK1 monoclonal antibody (M01A), clone 1E4
产品名称： BAK1 monoclonal antibody (M01A), clone 1E4
英文名称： BAK1 monoclonal antibody (M01A), clone 1E4
产品编号： H00000578-M01A
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant BAK1.
- Immunogen:
- BAK1 (AAH04431, 100 a.a. ~ 211 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- LQPTAENAYEYFTKIATSLFESGINWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHCIARWIAQRGGWVAALNLGNGPILNVLVVLGVVLLGQFVVRRFFKS
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgM Kappa
- Storage Buffer:
- In ascites fluid
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- MSDS:
Download
- Applications
- Immunoprecipitation
- Immunoprecipitation of BAK1 transfected lysate using anti-BAK1 monoclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with BAK1 MaxPab rabbit polyclonal antibody.
- Protocol Download
- Entrez GeneID:
- 578
- GeneBank Accession#:
- BC004431
- Protein Accession#:
- AAH04431
- Gene Name:
- BAK1
- Gene Alias:
- BAK,BAK-LIKE,BCL2L7,CDN1,MGC117255,MGC3887
- Gene Description:
- BCL2-antagonist/killer 1
- Omim ID:
- 600516
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq
- Other Designations:
- BCL2-like 7 protein,Bcl-2 homologous antagonist/killer,OTTHUMP00000016211,OTTHUMP00000039620,apoptosis regulator BAK,pro-apoptotic protein BAK
- Related Disease
- Adenocarcinoma
- Arthritis, Rheumatoid
- Ataxia Telangiectasia
- Autoimmune Diseases
- Cardiovascular Diseases
- Diabetes Mellitus, Type 2
- Disease Progression
- Edema
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Kidney Failure, Chronic
- Lung Neoplasms
- Lupus Erythematosus, Systemic
- Lymphoma, Non-Hodgkin
- Lymphoproliferative Disorders
- Pulmonary Disease, Chronic Obstructive
- Rheumatic Diseases
- Sjogren's Syndrome
- Urinary Bladder Neoplasms