FITC标记的颗粒酶K抗体
产品名称: FITC标记的颗粒酶K抗体
英文名称: Anti-Granzyme K/FITC
产品编号: HZ-6788R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: IF=1:50-200
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Rabbit Anti-Granzyme K/FITC Conjugated antibody
FITC标记的颗粒酶K抗体
英文名称 | Anti-Granzyme K/FITC |
中文名称 | FITC标记的颗粒酶K抗体 |
别 名 | Fragmentin 3; Fragmentin-3; Fragmentin3; GRAK_HUMAN; Granzyme 3; Granzyme K; Granzyme K precursor; Granzyme-3; Granzyme3; GranzymeK; GZMK; NK TRYP 2; NK TRYP2; NK tryptase 2; NK-TRYP-2; NK-tryptase-2; NKTRYP2; Serine protease granzyme 3; TRYP 2; TRYP2; Tryptase II; TryptaseII. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 免疫学 信号转导 细胞凋亡 转录调节因子 细胞外基质 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Horse, |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 26kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Granzyme K |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes. [provided by RefSeq, Jul 2008]. Subcellular Location: Secreted. Cytoplasmic granule. Tissue Specificity: Expressed in lung, spleen, thymus and peripheral blood leukocytes. Similarity: Belongs to the peptidase S1 family. Granzyme subfamily. Contains 1 peptidase S1 domain. Database links: Entrez Gene: 3003 Human Entrez Gene: 14945 Mouse Entrez Gene: 29165 Rat Omim: 600784 Human SwissProt: P49863 Human SwissProt: O35205 Mouse SwissProt: P49864 Rat Unigene: 277937 Human Unigene: 56993 Mouse Unigene: 11190 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因产物是来自细胞毒性淋巴细胞胞质颗粒的一组相关丝氨酸蛋白酶的成员。细胞溶解T淋巴细胞(CTL)和自然杀伤细胞(NK)具有识别、结合和裂解特定靶细胞的显著能力。它们被认为是通过溶解细胞表面的“非自身”抗原来保护宿主,通常是由细胞内病原体感染引起的肽或蛋白质。这里描述的蛋白质缺乏在其他颗粒酶中存在的N-糖基化的一致序列。[ RefSeq,JUL 2008 ]提供。