CSF1R/CEN5q FISH Probe
产品名称: CSF1R/CEN5q FISH Probe
英文名称: CSF1R/CEN5q FISH Probe
产品编号: FG0080
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Labeled FISH probes for identification of gene amplification using Fluoresecent In Situ Hybridization Technique. (Technology)
- Storage Instruction:
- Store at 4°C in the dark.
- Quality Control Testing:
- Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
- Supplied Product:
- DAPI Counterstain (1500 ng/mL ) 250 uL
- Note:
- Hybridization position of the probes on the chromosome:
-
- Probe 1:
Size:
Fluorophore:
Location: - CSF1R
Approximately 150kb
Texas Red
5q32
- Probe 2:
Size:
Fluorophore:
Location: - CEN5q
Approximately 700kb
FITC
5q11.2
- Probe Gap:
- The gap between two probes is approximately 96,720 kb.
- Origin:
- Human
- Source:
- Genomic DNA
- Regulation Status:
- For research use only (RUO)
- Applications
- Fluorescent In Situ Hybridization (Cell)
- Protocol Download
- Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge this image
- Human ovary cancer (FFPE) stained with CSF1R/CEN5q FISH Probe. Human ovary cancer showed no CSF1R gene amplification.
- Protocol Download
- Application Image
- Fluorescent In Situ Hybridization (Cell)
- Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Entrez GeneID:
- 1436
- Gene Name:
- CSF1R
- Gene Alias:
- C-FMS,CD115,CSFR,FIM2,FMS
- Gene Description:
- colony stimulating factor 1 receptor
- Omim ID:
- 164770
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. [provided by RefSeq
- Other Designations:
- CD115 antigen,FMS proto-oncogene,McDonough feline sarcoma viral (v-fms) oncogene homolog,macrophage colony stimulating factor I receptor,soluble CSF1R variant 1
- Interactome
- Related Disease
- Asthma
- Crohn's disease
- Genetic Predisposition to Disease
- Heart Defects, Congenital
- Lung Neoplasms
- Myelodysplastic Syndromes
- Pancreatic cancer
- Pancreatic Neoplasms
- Pulmonary Disease, Chronic Obstructive
- Purpura, Thrombocytopenic, Idiopathic
- Tobacco Use Disorder
- Urinary Bladder Neoplasms
- Werner syndrome