FITC标记的鸟氨酸氨基转移酶抗体
产品名称： FITC标记的鸟氨酸氨基转移酶抗体
英文名称： Anti-ornithine aminotransferase/FITC
产品编号： HZ-18036R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-ornithine aminotransferase/FITC Conjugated antibody
FITC标记的鸟氨酸氨基转移酶抗体
| 英文名称 | Anti-ornithine aminotransferase/FITC |
| 中文名称 | FITC标记的鸟氨酸氨基转移酶抗体 |
| 别 名 | GACR; Gyrate atrophy; HOGA; OAT_HUMAN; Ornithine aminotransferase, hepatic form; Ornithine aminotransferase, renal form; OAT; OATASE; OKT; Ornithine aminotransferase (gyrate atrophy); Ornithine aminotransferase mitochondrial; ornithine aminotransferase precursor; Ornithine aminotransferase, mitochondrial precursor; Ornithine delta aminotransferase; Ornithine oxo acid aminotransferase. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 信号转导 细胞类型标志物 新陈代谢 线粒体 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Pig, Cow, Horse, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 45kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ornithine aminotransferase |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: OAT (ornithine aminotransferase (mitochondrial), ornithine-oxo-acid aminotransferase) is a 439 amino acid protein encoded by the human gene OAT. OAT belongs to the class III pyridoxal-phosphate-dependent aminotransferase family and is usually found as a homotetramer in the mitochondrion matrix. OAT catalyzes the major catalytic reaction for ornithine. Ornithinemia, presumably due to deficiency of ornithine ketoacid aminotransferase (OAT) has been found in patients with gyrate atrophy of the choroid and retina. The clinical history of gyrate atrophy is usually night blindness that begins in late childhood, accompanied by sharply demarcated circular areas of chorioretinal atrophy. During the second and third decades the areas of atrophy enlarge. The hepatic cleavage product, hepatic OAT, is formed by cleaving a 25 amino acid transit peptide from the N-terminus of the OAT precursor. The renal form is produced by cleaving a 35 amino acid transit peptide from the N-terminus。 Function: Ornithine aminotransferase (OAT) is a key mitochondrial enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. OAT has also been linked with prostate cancer and alternatively activated macrophages Subcellular Location: Mitochondrion matrix. Database links: Entrez Gene: 4942 Human Entrez Gene: 426430 Chicken Entrez Gene: 505323 Cow Entrez Gene: 18242 Mouse Entrez Gene: 64313 Rat Omim: 613349 Human SwissProt: Q3ZCF5 Cow SwissProt: P04181 Human SwissProt: P29758 Mouse SwissProt: P04182 Rat Unigene: 523332 Human Unigene: 13694 Mouse Unigene: 1430 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
OAT（OAT（ORNTHINE AIMOTORASERA（Mitochonrial），Olnithine - Oxo-acid aminfersferase）is a 439 amine acid蛋白质encoed by the Human Gene Oat .Oat Belong to the Class III Pyridxel-Posphate - Dependent Ainotangferase Family and is usually found as a同性恋同性恋in the mitochonrion matrix .Oat Catalyzes the Major Cataly信通Reaction for Oniththine .“ORNITHAIEMIEMIEM，Pabmmably due to赤字of ornithine ketoadd aminprosferase（OAT）has been found in patients with gyarroid of the choroid and reina .The ClINICAL History of GyRate A吸引力is usually night paminess that beges in late childhood，accompanied by Sharply Peries of Chrioreinal Atropy .During the second and third decades of atopy enlarge .The heatic Cleavage Product，Heatic Oat，is formed by Cleaving a 25 amine acid transit pepperde from the N-Terus of the OAT前体。The Renal form is produced by Cleaving a 35 amine acid transit pepperde from the N-finalus .