TNFRSF10C polyclonal antibody
产品名称： TNFRSF10C polyclonal antibody
英文名称： TNFRSF10C polyclonal antibody
产品编号： PAB13081
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of TNFRSF10C.
- Immunogen:
- A synthetic peptide corresponding to amino acids in an extracellular domain of human TNFRSF10C.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Specificity:
- An approximate 65 KDa band can be detected. It is human, mouse, and rat reactive.
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family.
Degli-Esposti MA, Smolak PJ, Walczak H, Waugh J, Huang CP, DuBose RF, Goodwin RG, Smith CA.J Exp Med. 1997 Oct 6;186(7):1165-70.
- 2.
- An antagonist decoy receptor and a death domain-containing receptor for TRAIL.
Pan G, Ni J, Wei YF, Yu G, Gentz R, Dixit VM.Science. 1997 Aug 8;277(5327):815-8.
- 3.
- The receptor for the cytotoxic ligand TRAIL.
Pan G, O'Rourke K, Chinnaiyan AM, Gentz R, Ebner R, Ni J, Dixit VM.Science. 1997 Apr 4;276(5309):111-3.
- Entrez GeneID:
- 8794
- Protein Accession#:
- AF012536
- Gene Name:
- TNFRSF10C
- Gene Alias:
- CD263,DCR1,LIT,MGC149501,MGC149502,TRAILR3,TRID
- Gene Description:
- tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
- Omim ID:
- 603613
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq
- Other Designations:
- TNF related TRAIL receptor,TNF related apoptosis-inducing ligand receptor 3,TRAIL receptor 3,antagonist decoy receptor for TRAIL/Apo-2L,decoy receptor 1,decoy without an intracellular domain,lymphocyte inhibitor of TRAIL,tumor necrosis factor receptor sup