Anti-GLUT2/FITC Conjugated抗体-抗体-抗体-生物在线
上海钰博生物科技有限公司
Anti-GLUT2/FITC Conjugated抗体

Anti-GLUT2/FITC Conjugated抗体

商家询价

产品名称: Anti-GLUT2/FITC Conjugated抗体

英文名称: Anti-GLUT2/FITC

产品编号: YB--10379R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

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 Anti-GLUT2/FITC Conjugated抗体

产品编号 YB-10379R-FITC
英文名称 Anti-GLUT2/FITC
中文名称 FITC标记的葡萄糖转运蛋白2抗体
别    名 liver; Glucose Transporter 2; Glucose Transporter GLUT2; Glucose transporter type 2; Glucose transporter type 2 liver; GLUT-2; GLUT2; GLUT 2; GTR2_HUMAN; SLC2A2; Solute carrier family 2 (facilitated glucose transporter) member 2; Solute carrier family 2 facilitated glucose transporter member 2; Solute carrier family 2, facilitated glucose transporter member 2.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Horse, 
产品应用 Flow-Cyt=1:50-200 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 54kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GLUT2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Glucose transporter 2 isoform is an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. It mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. [provided by RefSeq, Jul 2008].

Function:
Facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Liver, insulin-producing beta cell, small intestine and kidney.

Post-translational modifications:
N-glycosylated; required for stability and retention at the cell surface of pancreatic beta cells.

DISEASE:
Defects in SLC2A2 are the cause of Fanconi-Bickel syndrome (FBS) [MIM:227810]. FBS is a rare, well-defined clinical entity, inherited in an autosomal recessive mode and characterized by hepatorenal glycogen accumulation, proximal renal tubular dysfunction, and impaired utilization of glucose and galactose.

Similarity:
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

Database links:

Entrez Gene: 6514 Human

Entrez Gene: 20526 Mouse

Entrez Gene: 25351 Rat

Omim: 138160 Human

SwissProt: P11168 Human

SwissProt: P14246 Mouse

SwissProt: P12336 Rat

Unigene: 167584 Human

Unigene: 18443 Mouse

Unigene: 89295 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications