CHIC2,CHIC2蛋白抗体

产品编号HZ-13901R
英文名称CHIC2
中文名称CHIC2蛋白抗体
别 名BrX-like translocated in leukemia; BTL; Chic2; CHIC2_HUMAN; Cystein-rich hydrophobic domain 2; Cysteine-rich hydrophobic domain 2 protein; MGC21173.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Chicken, Dog, Cow,
CHIC2,CHIC2蛋白抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量19kDa
细胞定位细胞核 细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human CHIC2
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
CHIC2,CHIC2蛋白抗体PubMedPubMed
产品介绍background:
This gene encodes a member of the CHIC family of proteins. The encoded protein contains a cysteine-rich hydrophobic (CHIC) motif, and is localized to vesicular structures and the plasma membrane. This gene is associated with some cases of acute myeloid leukemia. [provided by RefSeq, Jul 2008]

Subcellular Location:
Cell membrane. Cytoplasmic vesicle. Also present at a Golgi-like vesicular compartment and at scattered vesicles.

Post-translational modifications:
Palmitoylation in the CHIC motif is required for membrane association.

DISEASE:
Note=A chromosomal aberration involving CHIC2 is found in a form of acute myeloid leukemia (AML). Translocation t(4;12)(q12;p13) with ETV6.

Similarity:
Belongs to the CHIC family.

Gene ID:
26511

Database links:
Entrez Gene: 26511 Human
Entrez Gene: 74277 Mouse
SwissProt: Q9UKJ5 Human
SwissProt: Q9D9G3 Mouse
Unigene: 335393 Human
Unigene: 239814 Mouse

CHIC2,CHIC2蛋白抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.